Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856371 | 0.85 | ACACB (0.45) | ACACBLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL9856638 | 0.85 | ACACB (0.45) | ACACBLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL9856151 | 0.85 | ACACB (0.45) | ACACBLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL9856572 | 0.84 | ACACB (0.47) | ACACBLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL9856665 | 0.83 | ACACB (0.49) | ACACBLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL9856401 | 0.80 | L3MBTL1 (0.46) | ACACBLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL28904086 | 0.79 | MEN1 (0.59) | LMNATP53SMN1; SMN2NPC1TSHR | |
| SCHEMBL28232829 | 0.79 | LMNA (0.46) | LMNATP53SMN1; SMN2NPC1TSHR | |
| SCHEMBL27982971 | 0.79 | RAB9A (0.62) | LMNATP53SMN1; SMN2NPC1TSHR | |
| SCHEMBL28191611 | 0.77 | ALDH1A1 (0.47) | LMNATP53SMN1; SMN2NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | claimed |