Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28216167 | 0.78 | — | — | |
| SCHEMBL8905398 | 0.70 | — | — | |
| SCHEMBL30932999 | 0.58 | ALDH1A1 (0.33) | THRBATMALDH1A1KDM4EHTR1A | |
| Maleic Acid SCHEMBL28537821 | 0.54 | HCAR2 (0.60) | THRBATMALDH1A1KDM4EHSD17B10 | |
| Fumaric Acid SCHEMBL27547982 | 0.53 | TSHR (0.69) | THRBATMALDH1A1KDM4EHSD17B10 | |
| Maleic Acid SCHEMBL196426 | 0.53 | TSHR (0.69) | THRBATMALDH1A1KDM4EHSD17B10 | |
| Fumaric Acid SCHEMBL196427 | 0.53 | TSHR (0.69) | THRBATMALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6652488 | 0.52 | TSHR (0.40) | ALDH1A1HPGDHSD17B10 | |
| Maleic Acid SCHEMBL8927918 | 0.51 | HCAR2 (0.55) | THRBATMALDH1A1KDM4EHSD17B10 | |
| Fumaric Acid SCHEMBL8927919 | 0.51 | HCAR2 (0.55) | THRBATMALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263492-B1 | RETINOIDS, THEIR PREPARATION AND USE AS PHARMACEUTICAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | claimed |
| EP-0263492-A1 | Retinoids, their preparation and use as pharmaceutical compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1988-04-13 | — | — | EP | claimed |
| CN-1104676-A | Thermostable photopolymeric material for liquid crystal alignment | GOLD STAR CO (KR) | 1995-07-05 | — | — | CN | disclosed |