Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL9750366 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CYP2A6ALOX12TSHRTDP1 | |
| Butadiene SCHEMBL3389123 | 0.91 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1SIRT2SIRT1 | |
| Benzene SCHEMBL1448798 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| Butadiene SCHEMBL9296764 | 0.85 | SIRT2 (0.47) | ALDH1A1CYP2A6TSHRTDP1HSD17B10 | |
| Naphthalene SCHEMBL56790 | 0.85 | CYP2A6 (0.61) | ALDH1A1CYP2A6ALOX12TSHRTDP1 | |
| SCHEMBL29405187 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CYP2A6ALOX12TSHRTDP1 | |
| SCHEMBL7638 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CYP2A6ALOX12TSHRTDP1 | |
| SCHEMBL473080 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CYP2A6ALOX12TSHRTDP1 | |
| SCHEMBL1176773 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP2A6TSHRTDP1HSD17B10 | |
| Naphthalene SCHEMBL8512071 | 0.82 | CYP2A6 (0.57) | ALDH1A1CYP2A6ALOX12TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073365-A | Clinical and personal care articles enhanced by lubricants and adjuvants | ADVANCED POLYMER SYSTEMS (US) | 1991-12-17 | — | — | US | disclosed |