Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856891 | 0.86 | HTR2A (0.53) | HTR2AHRH1SLC6A9LMNAALDH1A1 | |
| SCHEMBL9857027 | 0.82 | HTR2A (0.49) | HTR2AHRH1SLC6A9LMNAALDH1A1 | |
| SCHEMBL9856945 | 0.79 | HTR2A (0.49) | HTR2AHRH1SLC6A9ALDH1A1UBE2N | |
| SCHEMBL9857006 | 0.77 | HTR2A (0.50) | HTR2AHRH1LMNACHRM2SLC6A2 | |
| Bicarbonate SCHEMBL9857226 | 0.76 | LMNA (0.45) | HTR2AHRH1SLC6A9LMNAALDH1A1 | |
| Bicarbonate SCHEMBL9857218 | 0.76 | LMNA (0.45) | HTR2AHRH1SLC6A9LMNAALDH1A1 | |
| SCHEMBL9856558 | 0.76 | HRH1 (0.45) | HTR2AHRH1SLC6A9L3MBTL1MBTD1 | |
| SCHEMBL9856740 | 0.75 | HTR2A (0.47) | HTR2AHRH1LMNACHRM2SLC6A2 | |
| SCHEMBL9856649 | 0.74 | HTR2A (0.41) | HTR2AHRH1SLC6A9LMNAALDH1A1 | |
| SCHEMBL9857080 | 0.74 | HTR2A (0.50) | HTR2AHRH1SLC6A9UBE2NCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |