Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857027 | 0.91 | HTR2A (0.49) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| SCHEMBL9856815 | 0.86 | SLC6A9 (0.54) | HTR2ASLC6A9SIGMAR1SLC6A4 | |
| SCHEMBL9857304 | 0.84 | TAAR1 (0.50) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| SCHEMBL9856860 | 0.82 | HTR2A (0.49) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| Bicarbonate SCHEMBL9857218 | 0.80 | LMNA (0.45) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| Bicarbonate SCHEMBL9857226 | 0.80 | LMNA (0.45) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| SCHEMBL9856741 | 0.79 | HTR2A (0.49) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| SCHEMBL9856702 | 0.79 | TAAR1 (0.49) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| SCHEMBL9856681 | 0.79 | HTR2A (0.45) | HTR2AHRH1UBE2NCHRM1SLC6A9 | |
| SCHEMBL9856558 | 0.79 | HRH1 (0.45) | HTR2AHRH1UBE2NCHRM1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |