Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528129 | 0.93 | TAAR1 (0.55) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9856595 | 0.88 | HTR2A (0.50) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL8384207 | 0.85 | HTR2A (0.60) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9856887 | 0.84 | HTR2A (0.49) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9857036 | 0.84 | HTR2A (0.49) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9857077 | 0.84 | HTR2A (0.49) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9856731 | 0.84 | SLC6A4 (0.55) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9856768 | 0.83 | TAAR1 (0.54) | SLC6A4TAAR1HTR2AHRH1SLC6A2 | |
| SCHEMBL9857406 | 0.82 | CYP2D6 (0.52) | SLC6A4HTR2AHRH1SLC6A2CARM1 | |
| SCHEMBL9856913 | 0.82 | HTR2A (0.46) | SLC6A4TAAR1HTR2AHRH1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |