Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856971 | 0.70 | KDM4E (0.38) | KDM4ERXFP1ALDH1A1NPSR1 | |
| SCHEMBL9967840 | 0.65 | KDM1A (0.47) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL23841323 | 0.64 | ALDH1A1 (0.40) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL7848329 | 0.63 | HTT (0.46) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL2732490 | 0.62 | KDM4E (0.72) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL11436470 | 0.62 | KDM4E (0.62) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL9856717 | 0.62 | TP53 (0.35) | RXFP1 | |
| SCHEMBL22820476 | 0.61 | KDM4E (0.47) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL16954859 | 0.61 | ALDH1A1 (0.45) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL24123876 | 0.59 | KDM4E (1.00) | KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |