Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1E | P28566 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857042 | 0.71 | SLC6A4 (0.48) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL9856776 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1RXFP1NPSR1 | |
| SCHEMBL18120367 | 0.67 | CYP2C19 (0.47) | KDM4EALDH1A1HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL9857121 | 0.67 | KDM4E (0.42) | KDM4ETAAR1ALDH1A1HTTCYP2C19 | |
| SCHEMBL12412421 | 0.65 | CYP2C19 (0.64) | KDM4EL3MBTL1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9856602 | 0.64 | CYP2D6 (0.45) | L3MBTL1TAAR1ALDH1A1HTTHTR2A | |
| SCHEMBL11542294 | 0.62 | ESR1 (0.46) | L3MBTL1ALDH1A1CYP2C19RAB9AATM | |
| SCHEMBL9856563 | 0.62 | TAAR1 (0.53) | L3MBTL1TAAR1HTTHTR2ACYP2C19 | |
| SCHEMBL19121266 | 0.62 | ALDH1A1 (0.51) | KDM4EL3MBTL1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11300314 | 0.62 | SLC5A2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |