Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993796 | 0.87 | FBP1 (0.42) | FBP1EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL7579999 | 0.87 | GAA (0.45) | GAALMNAALDH1A1FAAHMEN1 | |
| SCHEMBL6285525 | 0.75 | — | — | |
| SCHEMBL19003867 | 0.75 | EPHX1 (0.58) | ALDH1A1MEN1KMT2AEPHX1KDM4E | |
| SCHEMBL10083913 | 0.75 | — | — | |
| SCHEMBL19351854 | 0.75 | EPHX1 (0.58) | LMNAALDH1A1FAAHMEN1TSHR | |
| SCHEMBL8285334 | 0.74 | — | — | |
| SCHEMBL12245072 | 0.72 | — | — | |
| SCHEMBL6289555 | 0.72 | — | — | |
| SCHEMBL6290290 | 0.71 | EPHX1 (0.68) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001158-A | Nitrosoureas compounds preparation thereof and utilization thereof in anticancerous | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1991-03-19 | — | — | US | disclosed |