SCHEMBL7579999

SCHEMBL7579999

O=C(NCCCl)NCCCl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.45
LMNA P02545 1/20 0.45
ALDH1A1 P00352 4/20 0.43
TSHR P16473 2/20 0.43
FAAH O00519 2/20 0.43
MEN1 O00255 1/20 0.43
ABCB11 O95342 1/20 0.43
GSR P00390 1/20 0.43
HTT P42858 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
KMT2A Q03164 1/20 0.43
EPHX1 P07099 6/20 0.42
PRMT1 Q99873 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10083913 0.87
SCHEMBL19351854 0.87 EPHX1 (0.58) LMNAALDH1A1TSHRFAAHMEN1
SCHEMBL9856907 0.87 GAA (0.39) GAALMNAALDH1A1TSHRFAAH
SCHEMBL12245072 0.83
SCHEMBL11463947 0.83 EPHX1 (0.37) GAALMNAALDH1A1TSHRFAAH
SCHEMBL6047100 0.83 EPHX1 (0.68) ALDH1A1FAAHEPHX1MAPTHPGD
SCHEMBL11470826 0.83 EPHX1 (0.37) GAALMNAALDH1A1TSHRFAAH
SCHEMBL15547605 0.81 EPHX1 (0.50) ALDH1A1FAAHEPHX1PRMT1SMN1; SMN2
SCHEMBL16927525 0.81 FAAH (0.37) GAALMNAALDH1A1TSHRFAAH
SCHEMBL11150877 0.81 SIGMAR1 (0.40) GAALMNAALDH1A1TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3218061-B2 CARMUSTINE PHARMACEUTICAL COMPOSITION NAVINTA III INC (US) 2025-07-02 EP claimed
EP-3218061-B1 CARMUSTINE PHARMACEUTICAL COMPOSITION NAVINTA III INC (US) 2022-06-29 EP claimed
US-10342769-B2 Carmustine pharmaceutical composition NAVINTA III INC (US) 2019-07-09 US claimed
US-20190169116-A1 PROCESS FOR PREPARATION OF CARMUSTINE INTAS PHARMACEUTICALS LTD. (IN) 2019-06-06 US claimed
EP-3442941-A1 PROCESS FOR PREPARATION OF CARMUSTINE Intas Pharmaceuticals Limited (IN) 2019-02-20 EP claimed
WO-2017178910-A1 PROCESS FOR PREPARATION OF CARMUSTINE INTAS PHARMACEUTICALS LTD. (IN) 2017-10-19 WO claimed
WO-2017154019-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA MSN LABORATORIES PRIVATE LIMITED (IN) 2017-09-14 WO claimed
US-20160136116-A1 Carmustine Pharmaceutical Composition PROVIDENT BANK 2016-05-19 US claimed
US-4028410-A Process of preparing 1,3-bis(2-chloroethyl)-1-nitrosourea THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1977-06-07 US claimed
US-20250339390-A1 KIT FOR PREPARING INJECTABLE CARMUSTINE SOLUTIONS VIVUS LLC (US) 2025-11-06 US disclosed
EP-3883865-B2 SEAL OF A PORTION CAPSULE GCS GERMAN CAPSULE SOLUTION GMBH (DE) 2025-11-05 EP disclosed
EP-3464530-B1 CANDLE COMPRISING A COMPOSTABLE PLASTIC ELEMENT CUP CANDLE GMBH (DE) 2025-08-27 EP disclosed
EP-3218061-B2 CARMUSTINE PHARMACEUTICAL COMPOSITION NAVINTA III INC (US) 2025-07-02 EP disclosed
US-11865206-B2 Stable ready-to-use carmustine pharmaceutical composition EMCURE PHARMACEUTICALS LTD (IN) 2024-01-09 US disclosed
EP-0841912-A1 ANTITUMOR 2-AMINOCARBONYL-1,2-BIS(METHYLSULFONYL)-1-(SUBSTITUTED)HYDRAZINES YALE UNIVERSITY (US) 1998-05-20 EP disclosed
US-5637619-A Antitumor 2-aminocarbonyl-1, 2-bis(methylsulfonyl)-1-(substituted)hydrazines YALE UNIVERSITY (US) 1997-06-10 US disclosed
WO-1997002029-A1 ANTITUMOR 2-AMINOCARBONYL-1,2-BIS(METHYLSULFONYL)-1-(SUBSTITUTED)HYDRAZINES YALE UNIVERSITY (US) 1997-01-23 WO disclosed
US-4128538-A Crosslinking polymeric dye mordant composition reaction product of bisalkane or bisarene sulfonate and vinyl polymer EASTMAN KODAK COMPANY (US) 1978-12-05 US disclosed
US-4028410-A Process of preparing 1,3-bis(2-chloroethyl)-1-nitrosourea THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1977-06-07 US disclosed
US-4028410-A Process of preparing 1,3-bis(2-chloroethyl)-1-nitrosourea THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1977-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160136116-A1 Carmustine Pharmaceutical Composition MGMT, PAICS, CNR2 GAA 2189/4885LMNA 4408/4885ALDH1A1 951/4885
US-20190169116-A1 PROCESS FOR PREPARATION OF CARMUSTINE MGMT, UMPS, HNMT GAA 1650/4885LMNA 3511/4885ALDH1A1 1479/4885
US-10342769-B2 Carmustine pharmaceutical composition MGMT, PAICS, CNR2 GAA 2189/4885LMNA 4408/4885ALDH1A1 951/4885
US-20250339390-A1 KIT FOR PREPARING INJECTABLE CARMUSTINE SOLUTIONS KIT, BRAF, MEN1 GAA 2424/4885LMNA 3417/4885ALDH1A1 943/4885
US-11865206-B2 Stable ready-to-use carmustine pharmaceutical composition SLC5A7, MEN1, PAICS GAA 2101/4885LMNA 4155/4885ALDH1A1 945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.