Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HRH1 | P35367 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857236 | 0.81 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL14526719 | 0.81 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL8263713 | 0.81 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9857170 | 0.81 | HTR2A (0.43) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9856722 | 0.80 | HTR2A (0.51) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9856889 | 0.80 | TAAR1 (0.53) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9856174 | 0.78 | L3MBTL1 (0.51) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9856897 | 0.78 | SLC6A2 (0.57) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| Sulfuric Acid SCHEMBL9856918 | 0.77 | HTR2A (0.45) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| Sulfuric Acid SCHEMBL9856915 | 0.77 | HTR2A (0.45) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |