SCHEMBL9856921

SCHEMBL9856921

CCCOC(=O)c1ccc(C(=O)Oc2ccccc2)cc1.[NaH]

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.72
MAPT P10636 7/20 0.70
ALDH1A1 P00352 6/20 0.70
KMT2A Q03164 3/20 0.70
HPGD P15428 3/20 0.70
MEN1 O00255 2/20 0.70
THRB P10828 1/20 0.70
TDP1 Q9NUW8 2/20 0.60
ESR1 P03372 2/20 0.60
TSHR P16473 2/20 0.60
CHRM1 P11229 1/20 0.60
SLC6A2 P23975 1/20 0.60
KDR P35968 1/20 0.60
STS P08842 1/20 0.54
PRSS1 P07477 2/20 0.53
ACR P10323 2/20 0.53
TMPRSS15 P98073 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
PARP10 Q53GL7 1/20 0.50
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27872796 0.98 LMNA (0.74) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL23553004 0.94 LMNA (0.77) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL8208952 0.94 LMNA (0.77) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL9856535 0.91 MAPT (0.63) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL19373814 0.90 MAPT (0.70) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL15315055 0.89 LMNA (0.71) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL11856660 0.89 MAPT (0.64) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL9856537 0.88 MAPT (0.67) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL28777000 0.88 LMNA (0.68) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL4465574 0.86 LMNA (0.96) LMNAMAPTALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426217-A2 Bleach precursors UNILEVER N.V. (NL) 1991-05-08 EP claimed