SCHEMBL8208952

SCHEMBL8208952

CCCOC(=O)c1ccc(OC(=O)c2ccccc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.77
MAPT P10636 7/20 0.68
KMT2A Q03164 5/20 0.68
ALDH1A1 P00352 6/20 0.66
MEN1 O00255 3/20 0.66
HPGD P15428 2/20 0.66
THRB P10828 1/20 0.66
TDP1 Q9NUW8 3/20 0.60
TSHR P16473 3/20 0.60
ESR1 P03372 2/20 0.60
CHRM1 P11229 1/20 0.60
SLC6A2 P23975 1/20 0.60
KDR P35968 1/20 0.60
PARP10 Q53GL7 1/20 0.58
STS P08842 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.55
PKM P14618 1/20 0.55
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23553004 1.00 LMNA (0.77) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL15315055 0.95 LMNA (0.71) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL27872796 0.95 LMNA (0.74) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL9856921 0.94 LMNA (0.72) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL19373814 0.93 MAPT (0.70) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL9856538 0.91 MAPT (0.67) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL22462710 0.91 MAPT (0.67) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL10344296 0.89 ALDH1A1 (0.67) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL11856660 0.89 MAPT (0.64) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL130761 0.88 LMNA (1.00) LMNAMAPTKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115701994-A Injectable formulations 斯玛尔药物有限公司 2023-02-14 CN disclosed
US-11197874-B2 Use of an amphoteric chelating agent for preventing contact allergies PREVOR INTERNATIONAL (FR) 2021-12-14 US disclosed
US-20210275553-A1 USE OF A CREAM THAT PROTECTS AGAINST THE EFFECTS OF AGGRESSIVE CHEMICAL AGENTS IN CONTACT WITH THE SKIN PREVOR INTERNATIONAL (FR) 2021-09-09 US disclosed
US-10953024-B2 Use of a cream that protects against the effects of aggressive chemical agents in contact with the skin PREVOR INTERNATIONAL (FR) 2021-03-23 US disclosed
EP-2874661-B1 USE OF A CREAM THAT PROTECTS AGAINST THE EFFECTS OF AGGRESSIVE CHEMICAL AGENTS IN CONTACT WITH THE SKIN PREVOR INT (FR) 2018-08-08 EP disclosed
EP-2874604-B1 USE OF AN AMPHOTERIC CHELATING AGENT FOR PREVENTING CONTACT ALLERGIES PREVOR INT (FR) 2018-02-14 EP disclosed
US-20150202217-A1 USE OF AN AMPHOTERIC CHELATING AGENT FOR PREVENTING CONTACT ALLERGIES PREVOR INTERNATIONAL (FR) 2015-07-23 US disclosed
US-20150190357-A1 USE OF A CREAM THAT PROTECTS AGAINST THE EFFECTS OF AGGRESSIVE CHEMICAL AGENTS IN CONTACT WITH THE SKIN PREVOR INTERNATIONAL (FR) 2015-07-09 US disclosed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4444844-A LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY RICOH CO., LTD. (JP) 1984-04-24 US disclosed
US-4205073-A Anti-diarrheal anilino nicotinic acids and method of using same SCHERING CORPORATION (US) 1980-05-27 US disclosed
US-4029815-A Anti-diarrheal anthranilic acids SCHERING CORPORATION (US) 1977-06-14 US disclosed