Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857379 | 0.86 | SLC6A4 (0.42) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL9857102 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC6A2MEN1KMT2ALMNA | |
| SCHEMBL9856705 | 0.80 | HTR2A (0.47) | HTR2AHRH1SLC6A4SLC6A2LMNA | |
| SCHEMBL14526719 | 0.79 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL9857236 | 0.79 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL8263713 | 0.79 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL9856873 | 0.79 | SLC6A4 (0.50) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL9856889 | 0.78 | TAAR1 (0.53) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL9856722 | 0.78 | HTR2A (0.51) | HTR2AHRH1SLC6A4SLC6A2MEN1 | |
| SCHEMBL9856532 | 0.77 | SLC6A4 (0.58) | HTR2AHRH1SLC6A4SLC6A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |