Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488747 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPK1TDP1LMNAMAPT | |
| SCHEMBL10349772 | 0.74 | CHRM3 (0.50) | SIGMAR1LMNASLC18A3KMT2AMEN1 | |
| SCHEMBL408318 | 0.72 | KMT2A (0.66) | SIGMAR1SLC18A3KMT2AMEN1CYP2D6 | |
| Benzoic Acid SCHEMBL18838596 | 0.72 | TSHR (0.56) | ALDH1A1SIGMAR1LMNASLC18A3KMT2A | |
| SCHEMBL817420 | 0.71 | KDM1A (0.50) | SIGMAR1LMNASLC18A3KMT2AMEN1 | |
| SCHEMBL594567 | 0.71 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8124713 | 0.71 | LMNA (0.51) | ALDH1A1MAPK1TDP1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL227939 | 0.70 | KMT2A (0.69) | SIGMAR1SLC18A3KMT2AMEN1CYP2D6 | |
| Bromide SCHEMBL10968790 | 0.70 | KMT2A (0.64) | SIGMAR1SLC18A3KMT2AMEN1CYP2D6 | |
| Water SCHEMBL22462471 | 0.70 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420806-A1 | Phosphonic acids, process for preparation and use as an active pharmaceutical composition | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |