Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483021 | 0.84 | ATM (0.39) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL7132391 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL22228016 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL11547281 | 0.80 | ATM (0.42) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL11495507 | 0.80 | ATM (0.36) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL9206727 | 0.79 | — | — | |
| SCHEMBL12946906 | 0.77 | — | — | |
| SCHEMBL14967401 | 0.77 | LMNA (0.46) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL26830530 | 0.76 | ATM (0.42) | ALDH1A1LMNAHSD17B10ATMPOLB | |
| SCHEMBL9127588 | 0.76 | LMNA (0.44) | ALDH1A1LMNAHSD17B10ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109485661-B | Method for synthesizing benzoxazole-oxazole compound by [3+2] cycloaddition | 河南师范大学 | 2020-05-12 | — | — | CN | disclosed |
| EP-0413918-A2 | Method for the production of alkoxyalkylidenemalonic acid esters | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0332033-A2 | N-cyclopropyl anilines and their use in processes for the synthesis of 1-cyclopropyl-quinolone-carboxylic acids and their derivatives | BAYER AG (DE) | 1989-09-13 | — | — | EP | disclosed |