Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23758301 | 0.76 | LMNA (0.56) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9682712 | 0.75 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL3487387 | 0.73 | KMT2A (0.44) | TSHRKMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL9575027 | 0.72 | KMT2A (0.48) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11353115 | 0.69 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7513808 | 0.69 | LMNA (0.53) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9452118 | 0.69 | DPP7 (0.38) | LMNATDP1SMN1; SMN2 | |
| SCHEMBL20690179 | 0.69 | — | — | |
| SCHEMBL2639213 | 0.69 | — | — | |
| SCHEMBL10959845 | 0.68 | LMNA (0.51) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055521-A | A copolymer of an n-vinyl-2-pyrrolidone or methyl (meth)acry late telomer and an oligomer of a unsaturated monomer, a polyc ondensable monomer or a lactam | ATOCHEM (FR) | 1991-10-08 | — | — | US | disclosed |