Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856997 | 0.91 | PLK1 (0.59) | NR1H4TP53MAPTNPC1RAB9A | |
| SCHEMBL9712999 | 0.79 | SMPD1 (0.67) | SMPD1NR1H4MEN1KMT2ATP53 | |
| SCHEMBL9713298 | 0.78 | SMPD1 (0.60) | SMPD1NR1H4MEN1KMT2ATP53 | |
| SCHEMBL11325837 | 0.76 | SMPD1 (0.82) | SMPD1NR1H4KMT2ATHRBPLA2G4B | |
| SCHEMBL7051069 | 0.75 | SMPD1 (0.61) | SMPD1NR1H4MEN1KMT2ATP53 | |
| SCHEMBL28225521 | 0.75 | SMPD1 (1.00) | SMPD1NR1H4KMT2ATHRBPLA2G4B | |
| SCHEMBL31194774 | 0.75 | SMPD1 (0.80) | SMPD1NR1H4KMT2ATHRBPLA2G4B | |
| SCHEMBL28224821 | 0.75 | SMPD1 (1.00) | SMPD1NR1H4KMT2ATHRBPLA2G4B | |
| SCHEMBL28225796 | 0.75 | SMPD1 (1.00) | SMPD1NR1H4KMT2ATHRBPLA2G4B | |
| SCHEMBL9713045 | 0.74 | NR1H4 (0.73) | SMPD1NR1H4MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |