Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15281987 | 0.83 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10ALOX15KMT2A | |
| SCHEMBL15282179 | 0.82 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10ALOX15KMT2A | |
| SCHEMBL2460611 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10ALOX15KMT2A | |
| SCHEMBL15282009 | 0.79 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10KMT2AMAPT | |
| SCHEMBL7496761 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15KMT2A | |
| SCHEMBL1585638 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15KMT2A | |
| SCHEMBL13035426 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10ALOX15KMT2A | |
| SCHEMBL5419183 | 0.76 | ALOX15 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MAPT | |
| SCHEMBL4045864 | 0.76 | ALOX15 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MAPT | |
| SCHEMBL143815 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091040-A | Procedure for making trimethylolmethane | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1978-05-23 | — | — | US | claimed |
| CN-112441978-B | Preparation method of 1-methyl-5-hydroxypyrazole-4-carboxylic acid ethyl ester | 江西天宇化工有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-112441978-A | Preparation method of 1-methyl-5-hydroxypyrazole-4-carboxylic acid ethyl ester | 江西天宇化工有限公司 | 2021-03-05 | — | — | CN | disclosed |
| EP-0413918-A2 | Method for the production of alkoxyalkylidenemalonic acid esters | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0159599-B1 | PROCESS FOR THE PREPARATION OF ALCOXYMETHYLENE COMPOUNDS OF ESTERS OF ACETIC ACID AND SUBSTITUTED ACETIC ACID | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4665218-A | Method for the preparation of alkoxymethylene compounds of acetic esters and substituted acetic esters | DYNAMIT NOBEL AG (DE) | 1987-05-12 | — | — | US | disclosed |
| EP-0159599-A2 | Process for the preparation of alcoxymethylene compounds of esters of acetic acid and substituted acetic acid | HÜLS AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | disclosed |
| US-4091040-A | Procedure for making trimethylolmethane | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1978-05-23 | — | — | US | disclosed |