Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857573 | 0.73 | RNPEP (0.36) | RNPEPALDH1A1SLC7A5 | |
| SCHEMBL13618644 | 0.70 | MMP1 (0.33) | RNPEPALDH1A1MMP1MMP3MMP9 | |
| SCHEMBL19913368 | 0.69 | SLC1A3 (0.46) | RNPEPMMP1MMP2MMP3MMP9 | |
| SCHEMBL9857827 | 0.68 | SLC22A6 (0.33) | MAPT | |
| SCHEMBL2574576 | 0.67 | GABRR1 (0.44) | RNPEP | |
| SCHEMBL26771564 | 0.67 | CHRM1 (0.42) | RNPEP | |
| SCHEMBL8060386 | 0.66 | SMN1; SMN2 (0.55) | RNPEPALDH1A1MAPT | |
| SCHEMBL8060390 | 0.66 | SMN1; SMN2 (0.55) | RNPEPALDH1A1MAPT | |
| SCHEMBL5509970 | 0.66 | SLC22A6 (0.39) | MAPT | |
| SCHEMBL13588557 | 0.66 | SLC22A6 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072023-A | Reacting lactone with ester anion to form cyclohexenone ester; oxidizing or dehydrogenating the intermediate | E. R. SQUIBB & SONS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0442495-A1 | Process for preparing highly substituted phenyls | E.R. SQUIBB & SONS, INC. (US) | 1991-08-21 | — | — | EP | disclosed |