Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856763 | 0.90 | SLC6A4 (0.44) | SLC6A4DHFRCYP2D6KDM4EALDH1A1 | |
| SCHEMBL9857018 | 0.80 | SLC6A4 (0.46) | SLC6A4CHRM2CHRM1CHRM3ALDH1A1 | |
| SCHEMBL9856490 | 0.74 | CHRM2 (0.56) | SLC6A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL2907365 | 0.73 | CHRM2 (0.66) | DHFRCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL12377082 | 0.71 | CHRM2 (0.54) | DHFRCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL9856913 | 0.70 | HTR2A (0.46) | SLC6A4CYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL12960399 | 0.70 | KMT2A (0.49) | DHFRCYP2D6KDM4EALDH1A1MAPK1 | |
| SCHEMBL9857036 | 0.70 | HTR2A (0.49) | SLC6A4CYP2D6CHRM1ALDH1A1TSHR | |
| SCHEMBL8088241 | 0.70 | HTR1B (0.63) | CYP2D6KDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL8501910 | 0.68 | CHRM2 (0.57) | CYP2D6CHRM2CHRM1CHRM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |