Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348939 | 0.84 | ADRA1D (0.60) | NR1H4FFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL10719026 | 0.81 | NR1H4 (0.55) | NR1H4FFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL9351817 | 0.81 | ADRA1D (0.59) | NR1H4FFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL9857002 | 0.75 | CYSLTR2 (0.59) | NR1H4FFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL9857414 | 0.75 | NR1H4 (0.59) | NR1H4FFAR1CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL9171590 | 0.75 | ADRA1D (0.62) | — | |
| SCHEMBL9857021 | 0.75 | FFAR1 (0.63) | NR1H4FFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL9351304 | 0.73 | SMN1; SMN2 (0.63) | NR1H4 | |
| SCHEMBL9713250 | 0.73 | KCNMA1 (0.62) | NR1H4FFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL835506 | 0.72 | MEN1 (0.65) | NR1H4FFAR1S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |