Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857030 | 0.88 | LTA4H (0.53) | FFAR1S1PR1S1PR3S1PR5KDM4E | |
| SCHEMBL9712932 | 0.77 | POLB (0.61) | FFAR1S1PR1S1PR3S1PR5KDM4E | |
| SCHEMBL10721871 | 0.74 | FFAR1 (0.51) | FFAR1S1PR1S1PR3S1PR5KDM4E | |
| SCHEMBL947760 | 0.73 | S1PR1 (0.83) | FFAR1S1PR1S1PR3S1PR5LTA4H | |
| SCHEMBL1747055 | 0.73 | FFAR1 (0.74) | FFAR1S1PR1S1PR3S1PR5LTA4H | |
| SCHEMBL1746597 | 0.72 | FFAR1 (1.00) | FFAR1S1PR1S1PR3S1PR5LMNA | |
| SCHEMBL950975 | 0.72 | FFAR1 (0.71) | FFAR1S1PR1S1PR3S1PR5LTA4H | |
| SCHEMBL4656572 | 0.71 | FFAR1 (0.97) | FFAR1S1PR1S1PR3S1PR5LMNA | |
| SCHEMBL835506 | 0.71 | MEN1 (0.65) | FFAR1S1PR1S1PR3S1PR5LTA4H | |
| SCHEMBL1744514 | 0.71 | FFAR1 (0.65) | FFAR1S1PR1S1PR3S1PR5PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |