Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896275 | 0.78 | POLB (1.00) | POLBNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL9857397 | 0.77 | FFAR1 (0.55) | FFAR1S1PR1KDM4ES1PR3S1PR5 | |
| SCHEMBL3083461 | 0.77 | RAB9A (0.79) | FFAR1NPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL16242598 | 0.76 | POLB (0.87) | POLBNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL1586637 | 0.76 | HTR2A (0.66) | FFAR1NPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL11348028 | 0.76 | RAB9A (0.77) | FFAR1NPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL13959555 | 0.76 | FFAR1 (0.64) | FFAR1S1PR1S1PR3S1PR5PLA2G4B | |
| SCHEMBL9819860 | 0.76 | FFAR1 (0.64) | FFAR1NPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL4981505 | 0.75 | KCNA3 (0.73) | FFAR1NPC1RAB9AS1PR1S1PR3 | |
| SCHEMBL7298052 | 0.74 | POLB (0.65) | POLBNPC1RAB9AMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |