SCHEMBL9857403

SCHEMBL9857403

O=C(Oc1ccc(O)cc1-c1ccccc1)c1ccc(C(=O)Oc2ccc(O)cc2-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.56
ESR1 P03372 4/20 0.56
SERPINE1 P05121 1/20 0.47
EGFR P00533 1/20 0.47
SELL P14151 1/20 0.46
SELP P16109 1/20 0.46
ALOX5 P09917 1/20 0.46
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 2/20 0.44
ALDH1A1 P00352 1/20 0.44
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
MEN1 O00255 1/20 0.43
JAK2 O60674 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL767483 0.98 ESR1 (0.55) ESR2ESR1SERPINE1EGFRSELL
SCHEMBL9716693 0.95 ESR1 (0.56) ESR2ESR1SERPINE1EGFRSELL
SCHEMBL8849838 0.93 ESR1 (0.50) ESR2ESR1SERPINE1EGFRSELL
SCHEMBL777827 0.88 KMT2A (0.49) ESR2ESR1SERPINE1EGFRSELL
SCHEMBL27898043 0.85 RXRA (0.55) ESR2ESR1SERPINE1EGFRSELL
SCHEMBL777890 0.83 KMT2A (0.52) ESR2ESR1MAPTKMT2AMEN1
SCHEMBL9513770 0.82 BACE1 (0.56) ESR2ESR1ALOX5KMT2ALMNA
SCHEMBL14981353 0.81 KMT2A (0.53) ESR2ESR1MAPTKMT2ASMN1; SMN2
SCHEMBL29441965 0.81 PTGDR2 (0.58) ESR2ESR1SERPINE1EGFRSELL
SCHEMBL21583269 0.81 PTGDR2 (0.58) ESR2ESR1SERPINE1EGFRSELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0429654-A1 LIQUID-CRYSTAL POLYESTER CONTAINER AND MANUFACTURE THEREOF TOYO SEIKAN KAISHA, LTD. (JP) 1991-06-05 EP disclosed
EP-0314785-A1 BIAXIALLY ORIENTED POLYESTER FILM TORAY INDUSTRIES, INC. (JP) 1989-05-10 EP disclosed
US-4798875-A POLYESTER BLEND TORAY INDUSTRIES, INC. (JP) 1989-01-17 US disclosed
US-4699746-A Process of making high tenacity as-spun anisotropic melt fibers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-13 US disclosed
US-4612362-A Thermotropic polyester-carbonates containing 2,2-dimethyl-1,3-propanediol ALLIED CORPORATION (US) 1986-09-16 US disclosed
US-4612154-A Spinning of certain high molecular weight anisotropic melt forming polyesters E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-09-16 US disclosed
EP-0165073-A2 Improved spinning process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-12-18 EP disclosed
US-4435561-A Temperature stable thermotropic poly(ester carbonate) containing high amounts of readily available diols ALLIED CORPORATION (US) 1984-03-06 US disclosed
US-4398018-A Temperature stable thermotropic poly(ester carbonate) derived from t-butylhydroquinone ALLIED CORPORATION (US) 1983-08-09 US disclosed