Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SELL | P14151 | 1/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28123080 | 0.93 | RXRA (0.57) | RXRARXRBRXRGLMNAKMT2A | |
| SCHEMBL150516 | 0.90 | KMT2A (0.61) | RXRARXRBRXRGLMNAALDH1A1 | |
| SCHEMBL767483 | 0.87 | ESR1 (0.55) | RXRARXRBRXRGLMNAALDH1A1 | |
| SCHEMBL9857403 | 0.85 | ESR2 (0.56) | RXRARXRBRXRGLMNAALDH1A1 | |
| SCHEMBL5162031 | 0.84 | KMT2A (0.63) | LMNAKMT2AESR1ESR2MAPT | |
| SCHEMBL11761673 | 0.84 | KMT2A (0.50) | RXRARXRBRXRGLMNAALDH1A1 | |
| SCHEMBL29905087 | 0.84 | SERPINE1 (0.60) | LMNAKMT2AESR1ESR2MAPT | |
| SCHEMBL777827 | 0.83 | KMT2A (0.49) | LMNAALDH1A1KMT2AESR1ESR2 | |
| SCHEMBL8849838 | 0.82 | ESR1 (0.50) | LMNAALDH1A1KMT2AESR1ESR2 | |
| SCHEMBL9716693 | 0.81 | ESR1 (0.56) | RXRARXRBRXRGLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781426-B | Pharmaceutical composition for treating cutaneous burns | 45 SEC LLC | 2015-01-07 | — | — | CN | disclosed |
| CN-102781426-A | Pharmaceutical composition for treating cutaneous burns | 45 SEC LLC | 2012-11-14 | — | — | CN | disclosed |