SCHEMBL985753

SCHEMBL985753

CCC(Oc1cc(-c2nn(C)c(OC(F)F)c2Cl)c(F)cc1Cl)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.32
PPARG P37231 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
FABP4 P15090 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857238 0.87 KDM4E (0.36) PPARG
SCHEMBL27846988 0.85 PPOX (0.30)
SCHEMBL9870542 0.85
SCHEMBL38952 0.84 TDP1 (0.36) SMN1; SMN2
SCHEMBL4898211 0.84 TDP1 (0.36) SMN1; SMN2
SCHEMBL6295364 0.83 PPOX (0.46) SMN1; SMN2GAA
SCHEMBL27545557 0.83 CTSA (0.30)
SCHEMBL8338507 0.83 PDE4A (0.31)
SCHEMBL3725606 0.83 KDM4E (0.31) GAA
SCHEMBL9857297 0.82 PPOX (0.36) SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060009359-A1 Selective heteroaryloxy-acetamide-based herbicides FEUCHT DIETER 2006-01-12 US claimed
US-6849578-B1 Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
EP-1453377-A1 HERBICIDES BASED ON SUBSTITUTED CARBOXYLIC ACID ANILIDES Bayer CropScience AG (DE) 2004-09-08 EP claimed
EP-1429612-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE Bayer CropScience AG (DE) 2004-06-23 EP claimed
EP-1423009-A2 HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP claimed
EP-1423005-A1 HERBICIDAL MIXTURES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-06-02 EP claimed
EP-1372395-A1 HERBICIDES BASED ON SUBSTITUTED ARYL KETONES Bayer CropScience AG (DE) 2004-01-02 EP claimed
EP-1351571-A2 SELECTIVE HERBICIDES BASED UPON 2,6-DISUBSTITUTED PYRIDINE DERIVATIVES Bayer CropScience AG (DE) 2003-10-15 EP claimed
WO-2003047346-A1 HERBICIDES BASED ON SUBSTITUTED CARBOXYLIC ACID ANILIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-06-12 WO claimed
WO-2003026426-A1 HERBICIDES CONTAINING SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONE BAYER CROPSCIENCE AG (DE) 2003-04-03 WO claimed
EP-1221848-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES Bayer Aktiengesellschaft (DE) 2002-07-17 EP claimed
EP-0787429-B1 Application of a composition for regulating plant growth NIHON NOHYAKU CO LTD (JP) 2001-12-12 EP claimed
WO-2001035741-A2 SYNERGISTIC HERBICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
WO-2001035740-A2 SELECTIVE HERBICIDES BASED UPON 2,6-DISUBSTITUTED PYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-05-25 WO claimed
WO-2001022819-A1 SELECTIVE HERBICIDES ON THE BASIS OF N-ARYL-TRIAZOLINE(THI)ONES BAYER AKTIENGESELLSCHAFT (DE) 2001-04-05 WO claimed
EP-0784431-B1 SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL BAYER AG (DE) 2000-03-08 EP claimed
EP-0929221-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AG (DE) 1999-07-21 EP claimed
WO-1998012923-A1 SELECTIVE HERBICIDES BASED ON ARYLSULPHONYLAMINOCARBONYLTRIAZOLINONES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-02 WO claimed
EP-0784431-A1 SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL BAYER AG (DE) 1997-07-23 EP claimed
WO-1996010333-A1 SYNERGISTIC ACTIVE SUBSTANCE HERBICIDE COMBINATIONS WITH 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-5-(2-CHLOROPROPIONAMIDO)-4-NITROPYRAZOL BAYER AKTIENGESELLSCHAFT (DE) 1996-04-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009359-A1 Selective heteroaryloxy-acetamide-based herbicides AADAC, HACL2, HDHD5 PPARA 79/4885PPARG 38/4885SMN1; SMN2 3648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.