Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713940 | 0.92 | NR1H4 (0.52) | NR1H4NPC1RAB9AHDAC1MEN1 | |
| SCHEMBL9857044 | 0.88 | NR1H4 (0.59) | NR1H4NPC1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL9857326 | 0.88 | NR1H4 (0.51) | NR1H4NPC1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL9856852 | 0.87 | NR1H4 (0.58) | NR1H4NPC1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL9713930 | 0.85 | KCNMA1 (0.62) | NR1H4NPC1RAB9AHDAC1MEN1 | |
| SCHEMBL9857625 | 0.84 | NR1H4 (0.52) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9713649 | 0.83 | NR1H4 (0.63) | NR1H4NPC1RAB9AHDAC1SMN1; SMN2 | |
| SCHEMBL9713482 | 0.82 | NR1H4 (0.56) | NR1H4NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9857546 | 0.81 | NR1H4 (0.52) | NR1H4NPC1RAB9AHDAC1POLB | |
| SCHEMBL9857323 | 0.81 | NR1H4 (0.58) | NR1H4NPC1RAB9AHDAC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |