Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.51 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857021 | 0.91 | FFAR1 (0.63) | PLK1CYSLTR2CYSLTR1FFAR1NR1H4 | |
| SCHEMBL9713304 | 0.86 | PLK1 (0.53) | PLK1CACNA1HCACNA1BMEN1KMT2A | |
| SCHEMBL9857002 | 0.84 | CYSLTR2 (0.59) | PLK1CYSLTR2CYSLTR1FFAR1SLC16A3 | |
| SCHEMBL11347943 | 0.84 | NR1H4 (0.55) | SUCNR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1123608 | 0.81 | SENP7 (0.61) | PLK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9857410 | 0.78 | NR1H4 (0.53) | PLK1CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL9351817 | 0.76 | ADRA1D (0.59) | CACNA1HCACNA1BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL11326563 | 0.76 | MAPT (0.67) | PLK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9348939 | 0.75 | ADRA1D (0.60) | CACNA1HCYSLTR2CYSLTR1FFAR1NR1H4 | |
| SCHEMBL31661766 | 0.75 | SLC16A3 (0.54) | MEN1KMT2APPARASLC16A3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |