Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | POLG | P54098 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857986 | 0.95 | SLC22A6 (0.45) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9857669 | 0.84 | ABCB11 (0.36) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9858395 | 0.84 | ABCB11 (0.32) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9857680 | 0.84 | SLC22A6 (0.45) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9858137 | 0.83 | SLC22A6 (0.47) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9857984 | 0.81 | FAP (0.43) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9857663 | 0.80 | FAP (0.42) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9858339 | 0.79 | FGFR1 (0.50) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9858133 | 0.78 | FGFR1 (0.47) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9417160 | 0.77 | SLC22A6 (0.50) | SLC22A6ABCB11POLA1POLGFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |