Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 2/20 | 0.56 |
| ▸ | STK3 | Q13188 | 2/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858074 | 0.87 | ALDH1A1 (0.48) | STK4STK3LRRK2ALDH1A1HSD17B10 | |
| SCHEMBL8541928 | 0.87 | ALDH1A1 (0.61) | STK4STK3LRRK2ALDH1A1HSD17B10 | |
| SCHEMBL8921302 | 0.82 | ALDH1A1 (0.58) | STK4STK3LRRK2ALDH1A1HSD17B10 | |
| SCHEMBL9857773 | 0.82 | ALDH1A1 (0.52) | STK4STK3ALDH1A1HSD17B10HPGD | |
| SCHEMBL8546603 | 0.81 | ALDH1A1 (0.48) | STK4STK3LRRK2ALDH1A1HSD17B10 | |
| SCHEMBL9858082 | 0.81 | ALDH1A1 (0.48) | STK4STK3LRRK2ALDH1A1HSD17B10 | |
| SCHEMBL9857938 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDALOX15PRKDC | |
| SCHEMBL9857274 | 0.77 | ALDH1A1 (0.47) | STK3LRRK2ALDH1A1HSD17B10HPGD | |
| SCHEMBL9858081 | 0.76 | ALDH1A1 (0.47) | STK4STK3LRRK2ALDH1A1HSD17B10 | |
| SCHEMBL9857856 | 0.76 | ALDH1A1 (0.60) | STK4STK3LRRK2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |