Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | STK4 | Q13043 | 1/20 | 0.47 |
| ▸ | STK3 | Q13188 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858082 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10STK4 | |
| SCHEMBL9858074 | 0.90 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10STK4 | |
| SCHEMBL8541928 | 0.90 | ALDH1A1 (0.61) | ALDH1A1HPGDALOX15HSD17B10STK4 | |
| SCHEMBL8546603 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10STK4 | |
| SCHEMBL9857748 | 0.82 | STK4 (0.56) | ALDH1A1HPGDALOX15HSD17B10STK4 | |
| SCHEMBL9857938 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15HSD17B10POLB | |
| SCHEMBL9858268 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDALOX15HSD17B10POLB | |
| SCHEMBL9857274 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10STK3 | |
| SCHEMBL9858064 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10STK4 | |
| SCHEMBL9857985 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDALOX15HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |