Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963304 | 0.89 | FFAR4 (0.46) | MAOAMAOBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13159057 | 0.84 | CYP46A1 (0.43) | SMN1; SMN2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2471899 | 0.84 | HSD17B10 (0.52) | SMN1; SMN2ALDH1A1MAPTPOLBGAA | |
| SCHEMBL13159046 | 0.83 | KMT2A (0.48) | ALDH1A1MAPTPOLBNPC1RAB9A | |
| SCHEMBL20803212 | 0.83 | HSD17B10 (0.37) | SMN1; SMN2ALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL31363216 | 0.83 | HSD17B10 (0.37) | SMN1; SMN2ALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL9217561 | 0.83 | KDM4E (0.49) | ALDH1A1MAPTPOLBRAB9AHPGD | |
| SCHEMBL7759388 | 0.82 | SLC6A3 (0.59) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL11171592 | 0.82 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPTHPGDGAA | |
| SCHEMBL349432 | 0.79 | MAPT (0.51) | SMN1; SMN2ALDH1A1MAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068248-A | Analgesics, antipyretics and antiinflammatory agents | MERCK & CO., INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0160408-B1 | BENZOTHIOPHENES, THEIR PRODUCTION AND USE, AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1989-08-23 | — | — | EP | disclosed |