Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.52 |
| ▸ | PPARA | Q07869 | 15/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696339 | 0.89 | PPARA (0.58) | PPARGPPARA | |
| SCHEMBL15199292 | 0.83 | CTRC (0.53) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9614108 | 0.83 | PPARG (0.49) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9613979 | 0.83 | PPARG (0.63) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9614177 | 0.82 | PPARG (0.61) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9614187 | 0.80 | PPARG (0.55) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL11993061 | 0.80 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL27277079 | 0.79 | CTRC (0.56) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL10419468 | 0.79 | PPARG (0.67) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9614241 | 0.79 | PPARG (0.50) | PPARGPPARACTRCPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |