Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.58 |
| ▸ | PPARG | P37231 | 18/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11993061 | 0.91 | PPARG (0.62) | PPARAPPARG | |
| SCHEMBL9858176 | 0.89 | PPARG (0.52) | PPARAPPARG | |
| SCHEMBL9614051 | 0.85 | PPARA (0.67) | PPARAPPARG | |
| SCHEMBL9614120 | 0.84 | PPARA (0.66) | PPARAPPARG | |
| SCHEMBL9614013 | 0.84 | PPARA (0.66) | PPARAPPARG | |
| SCHEMBL15199292 | 0.83 | CTRC (0.53) | PPARAPPARG | |
| SCHEMBL9695320 | 0.81 | PPARA (0.80) | PPARAPPARG | |
| SCHEMBL10419185 | 0.81 | PPARA (0.78) | PPARAPPARG | |
| SCHEMBL9695302 | 0.81 | PPARA (0.78) | PPARAPPARG | |
| SCHEMBL9697457 | 0.81 | PPARA (0.78) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017435-A1 | OPTICALLY ACTIVE CARBOXYLIC ACIDS AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-15 | — | — | WO | disclosed |
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |