Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 5/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | STK4 | Q13043 | 1/20 | 0.40 |
| ▸ | STK3 | Q13188 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541928 | 0.84 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10ALOX15KMT2A | |
| SCHEMBL9857856 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10ALOX15KMT2A | |
| SCHEMBL9858064 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10ALOX15MEN1 | |
| SCHEMBL9857315 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10ALOX15MEN1 | |
| SCHEMBL9857773 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDHSD17B10ALOX15MEN1 | |
| SCHEMBL9857298 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10ALOX15MEN1 | |
| SCHEMBL9858266 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10ALOX15MEN1 | |
| SCHEMBL9858074 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10ALOX15MEN1 | |
| SCHEMBL8546603 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10ALOX15LRRK2 | |
| SCHEMBL9858082 | 0.74 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |