Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858369 | 1.00 | MGAM (0.35) | MGAMSICYP3A4 | |
| SCHEMBL9858372 | 1.00 | MGAM (0.35) | MGAMSICYP3A4 | |
| SCHEMBL9114861 | 0.82 | — | — | |
| SCHEMBL9143771 | 0.79 | — | — | |
| SCHEMBL14390244 | 0.79 | — | — | |
| SCHEMBL17036627 | 0.76 | — | — | |
| SCHEMBL8767596 | 0.74 | AKR1B1 (0.31) | — | |
| SCHEMBL14993757 | 0.71 | KEAP1 (0.35) | — | |
| SCHEMBL4872030 | 0.68 | — | — | |
| SCHEMBL172436 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | INSTITUTE OF CATALYSIS (CSIC) (ES) | 2012-09-13 | — | — | US | disclosed |
| WO-2010105851-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-23 | — | — | WO | disclosed |
| US-5036009-A | Biochemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-07-30 | — | — | US | disclosed |
| US-4508822-A | Biochemical process | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-04-02 | — | — | US | disclosed |
| EP-0076606-A1 | Biochemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | SI, GUSB, MPI | MGAM 112/4885SI 1/4885CYP3A4 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.