SCHEMBL9858653

SCHEMBL9858653

CC(C)(C)c1ccc(C(C)(C)CCC=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.41
LMNA P02545 1/20 0.38
TYR P14679 1/20 0.38
ALDH1A1 P00352 4/20 0.36
BCHE P06276 4/20 0.35
ACHE P22303 4/20 0.35
HDAC1 Q13547 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
HIF1A Q16665 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
EPHX2 P34913 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
SRD5A2 P31213 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858398 0.86 TSHR (0.43) TSHRTP53LMNAALDH1A1BCHE
SCHEMBL1832904 0.84 MEN1 (0.36) TSHRTP53LMNASMN1; SMN2MEN1
SCHEMBL6823447 0.84 SHBG (0.52) TSHRLMNATYRALDH1A1MEN1
SCHEMBL1834441 0.83 TAAR1 (0.48) ALDH1A1HDAC1HTTKMT2AHIF1A
SCHEMBL6826320 0.81 ALDH1A1 (0.42) LMNAALDH1A1MEN1KMT2ANPC1
SCHEMBL10549168 0.78 NQO1 (0.47) TSHRALDH1A1HTTKMT2ANPC1
SCHEMBL66122 0.75 TP53 (0.52) TSHRTP53LMNAEPHX2NR1H4
SCHEMBL1864936 0.75 TP53 (0.52) TSHRTP53LMNAEPHX2NR1H4
SCHEMBL6826195 0.74 ESR1 (0.52)
Methane SCHEMBL9798334 0.73 TP53 (0.50) TSHRTP53LMNAEPHX2NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291849-B1 4-METHYL-4-PHENYL-PENTAN-1-ALS, THEIR PREPARATION AND APPLICATION AS AROMA CHEMICALS BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
US-4837201-A 4-Methyl-4-phenyl-1-pentanals, their preparation and their use as scents BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US claimed
EP-0291849-A2 4-Methyl-4-phenyl-pentan-1-als, their preparation and application as aroma chemicals BASF Aktiengesellschaft (DE) 1988-11-23 EP claimed
EP-0291849-B1 4-METHYL-4-PHENYL-PENTAN-1-ALS, THEIR PREPARATION AND APPLICATION AS AROMA CHEMICALS BASF Aktiengesellschaft (DE) 1991-10-16 EP disclosed
US-4837201-A 4-Methyl-4-phenyl-1-pentanals, their preparation and their use as scents BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0291849-A2 4-Methyl-4-phenyl-pentan-1-als, their preparation and application as aroma chemicals BASF Aktiengesellschaft (DE) 1988-11-23 EP disclosed