Acrylic Acid

Acrylic Acid

SCHEMBL9858758

C=CC(=O)O.NC(N)COCC(N)N

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
HSD17B10 Q99714 2/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 5/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
BLM P54132 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MEN1 O00255 1/20 0.35
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 3/20 0.33
TP53 P04637 2/20 0.33
HIF1A Q16665 2/20 0.33
FGFR4 P22455 1/20 0.33
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
GABRP O00591 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8658808 0.77 FFAR3 (0.39) LMNAALOX15TSHRBLMALDH1A1
Acrylic Acid SCHEMBL3646842 0.76 TSHR (0.56) LMNAHSD17B10ALOX15TSHRALDH1A1
Acrylic Acid SCHEMBL11078211 0.74 LMNA (0.46) LMNAHSD17B10ALOX15TSHRSLC6A2
SCHEMBL301646 0.72
SCHEMBL187961 0.71
Acrylic Acid SCHEMBL1881210 0.71
Acrylic Acid SCHEMBL6266430 0.71 LMNA (0.62) LMNAHSD17B10ALOX15TSHRSLC6A2
Acrylic Acid SCHEMBL17458932 0.71
Acrylic Acid SCHEMBL25388769 0.70 LMNA (0.53) LMNAHSD17B10ALOX15TSHRSLC6A2
Acrylic Acid SCHEMBL8019473 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075503-A Epoxy curing agent;chain extension for polyureas TEXACO CHEMICAL COMPANY (US) 1991-12-24 US disclosed