Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 known ✓ | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 known ✓ | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 known ✓ | P35228 | 2/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL20534091 | 0.84 | NOS3 (0.41) | FFAR3LCKFYNNOS3NOS1 | |
| Acetic Acid SCHEMBL15419481 | 0.83 | ALDH1A1 (0.41) | NOS3NOS1NOS2SLC7A5TSHR | |
| Acetic Acid SCHEMBL8414155 | 0.80 | ALDH1A1 (0.68) | NOS3NOS1NOS2TSHRALDH1A1 | |
| SCHEMBL301646 | 0.78 | — | — | |
| Acrylic Acid SCHEMBL9858758 | 0.77 | LMNA (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Phosphonic Acid SCHEMBL407924 | 0.74 | — | — | |
| Acetic Acid SCHEMBL5698774 | 0.74 | TSHR (0.46) | FFAR3LCKFYNSLC7A5TSHR | |
| Acetic Acid SCHEMBL5570292 | 0.73 | FFAR3 (0.47) | FFAR3LCKFYNGABRPGABRD | |
| Acetic Acid SCHEMBL6280777 | 0.73 | — | — | |
| Acetic Acid SCHEMBL10874504 | 0.73 | FFAR3 (0.47) | FFAR3LCKFYNGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110029151-B | Additive composition for loop-mediated isothermal amplification reaction | 台达电子国际（新加坡）私人有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-113316574-B | SHP2 inhibitor and application thereof | 贝达药业股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117230322-A | Method and system for efficiently extracting lithium from mixed salt solution | 苏州工业园区蒙纳士科学技术研究院 | 2023-12-15 | — | — | CN | disclosed |
| CN-110029151-B | Additive composition for loop-mediated isothermal amplification reaction | 台达电子国际（新加坡）私人有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-5772699-A | INCLUDING DICARBOXYLIC ACIDS AND AMINOCARBOXYLATE CHELATING AGENTS | CROMPTON & KNOWLES CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |
| US-4067836-A | ETHYLENE POLYMER, AUTO-OXIDATIVE COMPOUND, METAL SALTS | UNION CARBIDE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3935141-A | METAL SALT, ANTIOXIDANT | UNION CARBIDE CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |