SCHEMBL7028825

SCHEMBL7028825

CCCc1cccc(C(=O)c2cccc(CCC)c2O)c1O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.51
IAPP P10997 4/20 0.49
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
PRKCI P41743 1/20 0.47
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
KMT2A Q03164 1/20 0.43
ELANE P08246 2/20 0.43
CTSG P08311 1/20 0.43
ALOX5 P09917 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6931398 0.88 HMGB1 (0.49) HMGB1IAPPGABRA1GABRB2PRKCI
SCHEMBL8124725 0.87 PRKCI (0.54) HMGB1IAPPGABRA1GABRB2PRKCI
SCHEMBL9859 0.87 HMGB1 (0.69) HMGB1IAPPGABRA1GABRB2PRKCI
SCHEMBL16949829 0.86 GABRA1 (0.67) HMGB1IAPPGABRA1GABRB2CYP3A4
SCHEMBL14588767 0.85 HMGB1 (0.49) HMGB1IAPPGABRA1GABRB2PRKCI
Bicarbonate SCHEMBL22573123 0.85 HMGB1 (0.67) HMGB1IAPPGABRA1GABRB2PRKCI
Bicarbonate SCHEMBL236594 0.85 HMGB1 (0.67) HMGB1IAPPGABRA1GABRB2PRKCI
SCHEMBL9740139 0.84 HMGB1 (0.47) HMGB1IAPPGABRA1GABRB2PRKCI
SCHEMBL11215357 0.84 HMGB1 (0.47) HMGB1IAPPGABRA1GABRB2PRKCI
SCHEMBL416813 0.84 HMGB1 (0.47) HMGB1IAPPGABRA1GABRB2PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933343-B1 Method for producing sized, coated ceramic fibers COI CERAMICS INC (US) 2003-06-25 EP claimed
US-6251520-B1 APPLYING NON-AQUEOUS SIZING TO CERAMIC FIBER; CURING DOW CORNING CORPORATION 2001-06-26 US claimed
EP-0933343-A1 Method for producing sized, coated ceramic fibers DOW CORNING CORPORATION (US) 1999-08-04 EP claimed
CN-114868048-A Optical film, optical laminate, functional glass, and head-up display 日本化药株式会社 2022-08-05 CN disclosed
CN-113140453-A Method for manufacturing semiconductor structure 台湾积体电路制造股份有限公司 2021-07-20 CN disclosed
EP-0933343-B1 Method for producing sized, coated ceramic fibers COI CERAMICS INC (US) 2003-06-25 EP disclosed
US-6251520-B1 APPLYING NON-AQUEOUS SIZING TO CERAMIC FIBER; CURING DOW CORNING CORPORATION 2001-06-26 US disclosed
EP-0933343-A1 Method for producing sized, coated ceramic fibers DOW CORNING CORPORATION (US) 1999-08-04 EP disclosed
EP-0487121-B1 Optical fibre element comprising a polyacrylate coating layer reticulated by UV radiation and an H2-absorbing buffer PIRELLI CAVI SPA (IT) 1996-08-28 EP disclosed
US-5179619-A Multilayer coatings with photoinitiators PIRELLI CAVI S.P.A. (IT) 1993-01-12 US disclosed
EP-0487121-A1 Optical fibre element comprising a polyacrylate coating layer reticulated by UV radiation and an H2-absorbing buffer PIRELLI CAVI S.p.A. (IT) 1992-05-27 EP disclosed