Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471789 | 0.81 | CYP3A4 (0.42) | CYP3A4ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL2301047 | 0.78 | CYP3A4 (0.69) | CYP3A4ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL19461660 | 0.76 | CYP3A4 (0.36) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL29648867 | 0.76 | CYP3A4 (0.42) | CYP3A4ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL628189 | 0.76 | CYP3A4 (0.42) | CYP3A4ALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL682486 | 0.73 | MAPK1 (0.43) | ALDH1A1HPGDTDP1MAPT | |
| SCHEMBL1021390 | 0.72 | DGAT1 (0.40) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL1457695 | 0.71 | HSP90AA1 (0.41) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL19458942 | 0.71 | MAPK1 (0.41) | ALDH1A1HPGDTDP1MAPT | |
| SCHEMBL11533450 | 0.71 | MAPK1 (0.40) | CYP3A4ALDH1A1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153127-B1 | N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4863947-A | PESTICIDES, INSECTICIDES | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0058424-B1 | PYRAZOLINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4464386-A | Insecticidal 3-difluoromethoxyphenyl-1-phenylcarbamoyl-2-pyrazolines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0058424-A2 | Pyrazoline derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1982-08-25 | — | — | EP | disclosed |