Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544344 | 0.88 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL9311096 | 0.88 | AGTR1 (0.33) | AGTR1 | |
| SCHEMBL9311241 | 0.87 | AGTR1 (0.35) | ABCG2AGTR1 | |
| SCHEMBL9859327 | 0.84 | KDM4E (0.33) | ABCG2AGTR1ELANE | |
| SCHEMBL8544342 | 0.84 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL9311085 | 0.81 | FGFR1 (0.38) | AGTR1 | |
| SCHEMBL9309617 | 0.80 | MAPT (0.34) | AGTR1 | |
| SCHEMBL9311092 | 0.75 | POLB (0.35) | — | |
| SCHEMBL8545586 | 0.75 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9846770 | 0.75 | NPC1 (0.36) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |