Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168288 | 0.83 | LMNA (0.42) | LMNAMAOAPTGS1SCN4AMTNR1A | |
| SCHEMBL11795671 | 0.82 | LMNA (0.47) | LMNAMAOAPTGS1SCN4AMTNR1A | |
| SCHEMBL15611441 | 0.80 | BTK (0.33) | — | |
| SCHEMBL23239453 | 0.79 | LMNA (0.53) | LMNAMAOAPTGS1SCN4AMTNR1A | |
| SCHEMBL20995920 | 0.78 | LMNA (0.52) | LMNAMAOAPTGS1SCN4ALTA4H | |
| SCHEMBL14587067 | 0.78 | LMNA (0.52) | LMNAMAOAPTGS1SCN4ALTA4H | |
| SCHEMBL17395999 | 0.77 | LMNA (0.50) | LMNAMAOAPTGS1SCN4ALTA4H | |
| SCHEMBL8426711 | 0.77 | LMNA (0.50) | LMNAMAOAPTGS1SCN4ALTA4H | |
| SCHEMBL15668135 | 0.77 | LMNA (0.50) | LMNAMAOAPTGS1SCN4ALTA4H | |
| SCHEMBL2780133 | 0.76 | THRB (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447115-A1 | Polyvinylether composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |