SCHEMBL9859423

SCHEMBL9859423

C=COc1ccccc1OCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.55
CYP2C19 P33261 3/20 0.55
CYP2C9 P11712 2/20 0.55
L3MBTL1 Q9Y468 5/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 3/20 0.43
LTA4H P09960 2/20 0.43
CYP19A1 P11511 1/20 0.43
GAA P10253 1/20 0.43
CYP2D6 P10635 1/20 0.42
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
NR1I2 O75469 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADRA2A P08913 1/20 0.41
OPRK1 P41145 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dibutoxybenzene SCHEMBL1226749 0.84 CYP1A2 (0.72) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
1,2-Dibutoxybenzene SCHEMBL29428927 0.84 CYP1A2 (0.72) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
SCHEMBL9860366 0.82 ALDH1A1 (0.50) CYP1A2CYP2C19L3MBTL1TDP1GAA
1,2-Dibutoxybenzene SCHEMBL6236324 0.82 CYP1A2 (0.69) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
1-Allyloxy-2-Butoxybenzene SCHEMBL2847372 0.81 CYP1A2 (0.55) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
SCHEMBL195491 0.81 CYP1A2 (0.55) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
SCHEMBL8218661 0.80 CYP1A2 (0.53) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
SCHEMBL8218662 0.80 CYP1A2 (0.53) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
1-Propoxy-2-Butoxybenzene SCHEMBL2846696 0.80 CYP1A2 (0.67) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A
SCHEMBL406835 0.79 CYP1A2 (0.56) CYP1A2CYP2C19CYP2C9L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447115-A1 Polyvinylether composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-18 EP disclosed