SCHEMBL9860366

SCHEMBL9860366

C=COc1ccccc1OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
L3MBTL1 Q9Y468 8/20 0.48
MAPT P10636 3/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GLA P06280 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALOX15 P16050 1/20 0.42
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
KDM4E B2RXH2 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
HPGD P15428 1/20 0.40
GAA P10253 1/20 0.40
HCRTR1 O43613 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9859423 0.82 CYP1A2 (0.55) L3MBTL1MAPTNPSR1TDP1CYP1A2
SCHEMBL3113317 0.82 ADRA2B (0.43) ALDH1A1TDP1KDM4EHPGDGAA
SCHEMBL29592755 0.82 ADRA2B (0.43) ALDH1A1TDP1KDM4EHPGDGAA
1,2-Diethoxybenzene SCHEMBL29428929 0.82 ALDH1A1 (0.68) ALDH1A1L3MBTL1MAPTNPSR1GLA
1,2-Diethoxybenzene SCHEMBL578986 0.82 ALDH1A1 (0.68) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL28028354 0.81 ALDH1A1 (0.52) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL7994462 0.80 ALDH1A1 (0.43) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL2096024 0.79 L3MBTL1 (0.53) ALDH1A1L3MBTL1MAPTNPSR1GLA
1-Allyloxy-2-Ethoxybenzene SCHEMBL11755537 0.79 HPGD (0.51) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL9619092 0.78 ALDH1A1 (0.36) ALDH1A1L3MBTL1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0105341-B1 VINYLOXY-FUNCTIONAL ORGANOPOLYSILOXANES COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1987-01-07 EP claimed
EP-0447115-A1 Polyvinylether composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-18 EP disclosed
US-4177179-A ACRYLIC COPOLYMER AND EPOXY COMPOUND TOYO SODA MANUFACTURING CO., LTD. (JP) 1979-12-04 US disclosed