Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308810 | 0.83 | KDM4E (0.38) | ALDH1A1KDM4ECYP1A2CYP3A4HSD17B10 | |
| SCHEMBL7441078 | 0.83 | KDM4E (0.34) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL9571377 | 0.82 | KMT2A (0.34) | ALDH1A1KDM4EMYCWDR5CYP1A2 | |
| SCHEMBL9316514 | 0.81 | CYP3A4 (0.38) | ALDH1A1KDM4EMYCWDR5CYP1A2 | |
| SCHEMBL9311398 | 0.81 | PTGES (0.32) | ALDH1A1KDM4EMYCWDR5HSD17B10 | |
| SCHEMBL9311075 | 0.76 | MAOB (0.32) | MYCWDR5KMT2A | |
| SCHEMBL9310253 | 0.74 | PTGES (0.35) | ALDH1A1MYCWDR5CYP1A2CYP3A4 | |
| SCHEMBL9311082 | 0.74 | PTGES (0.35) | ALDH1A1MYCWDR5CYP1A2CYP3A4 | |
| SCHEMBL9316521 | 0.74 | FGFR3 (0.34) | ALDH1A1KDM4EMYCWDR5CYP1A2 | |
| SCHEMBL27370071 | 0.74 | CYP1A2 (0.34) | ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |