Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312055 | 0.89 | AR (0.38) | KDM4EMAPTKCNH2ALDH1A1HPGD | |
| SCHEMBL9308247 | 0.84 | KCNH2 (0.46) | KDM4EMAPTKCNH2ALDH1A1HPGD | |
| SCHEMBL9859487 | 0.83 | ALDH1A1 (0.32) | KDM4EALDH1A1HPGDKMT2ACYP3A4 | |
| SCHEMBL9309635 | 0.82 | CSNK2A2 (0.40) | KDM4EMAPTKCNH2ALDH1A1HPGD | |
| SCHEMBL9309957 | 0.80 | MAPT (0.41) | KDM4EMAPTKCNH2ALDH1A1HPGD | |
| SCHEMBL9308818 | 0.78 | KDM4E (0.34) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL9308252 | 0.74 | TSHR (0.37) | KDM4EMAPTKCNH2ALDH1A1HPGD | |
| SCHEMBL9309638 | 0.72 | PTGES (0.36) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL9312060 | 0.72 | AR (0.39) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9309961 | 0.70 | AR (0.34) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |