Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534914 | 0.83 | GPR119 (0.47) | PDE3BPDE3AGPR119PGRALDH1A1 | |
| SCHEMBL11530327 | 0.81 | PDE3B (0.45) | PDE3BPDE3AALDH1A1CA1CA2 | |
| SCHEMBL19656766 | 0.81 | PDE3B (0.64) | PDE3BPDE3AMAOBGPR119PGR | |
| SCHEMBL19656773 | 0.78 | PDE3B (0.50) | PDE3BPDE3AGPR119PGRPDE4A | |
| SCHEMBL26115222 | 0.77 | ALDH1A1 (0.34) | MAOBGPR119PGRALDH1A1HPGD | |
| SCHEMBL9392792 | 0.76 | HTT (0.49) | MAOBALDH1A1HPGDKDM4EHTT | |
| SCHEMBL17446924 | 0.76 | PDE3B (0.48) | PDE3BPDE3AMAOBGPR119PDE4A | |
| SCHEMBL18611205 | 0.76 | HSP90AA1 (0.42) | ALDH1A1HPGDKDM4EPDE4DHTT | |
| SCHEMBL11571863 | 0.76 | PDE3B (0.71) | PDE3BPDE3AGPR119PDE4APDE4B | |
| SCHEMBL16157007 | 0.76 | PDE3B (0.71) | PDE3BPDE3AGPR119PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153127-B1 | N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4863947-A | PESTICIDES, INSECTICIDES | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |
| US-4140787-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |