Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162470 | 0.86 | ALDH1A1 (0.49) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL4252448 | 0.78 | SMN1; SMN2 (0.66) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL4425568 | 0.77 | ERCC1 (0.49) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL5461862 | 0.76 | GAA (0.67) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL1548586 | 0.75 | TP53 (0.62) | KDM4EGAAALDH1A1HSD17B10HPGD | |
| SCHEMBL4253425 | 0.75 | KDM4E (0.79) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL5011339 | 0.75 | KDM4E (0.59) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL1548567 | 0.73 | GAA (0.53) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL5011466 | 0.73 | KDM4E (0.62) | KDM4ELMNAGAAALDH1A1HSD17B10 | |
| SCHEMBL328468 | 0.71 | KDM4E (0.49) | KDM4ELMNAGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071973-A | PROCESS FOR PREPARING OF NON-THROMBOGENIC SUBSTRATES | KELLER RUPRECHT (DE) | 1991-12-10 | — | — | US | disclosed |